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Document type:
Zeitschriftenartikel / Journal Article
Title:
Methods for quantitative evaluation of dynamics of repair proteins within irradiated cells
Collection editors:
Neumann, Reinhard; Apel, Pavel; Toulemonde, Marcel; Trautmann, Christina
Title of conference publication:
Swift Heavy Ions in Matter
Subtitle of conference publication:
Proceedings of the Sixth International Symposium on Swift Heavy Ions in Matter (SHIM 2005)
Journal:
Nuclear Instruments and Methods in Physics Research Section B
Volume:
245
Issue:
1
Conference title:
International Symposium on Swift Heavy Ions in Matter (6., 2005, Aschaffenburg)
Venue:
Aschaffenburg, Germany
Year of conference:
2005
Date of conference beginning:
28.05.2005
Date of conference ending:
31.05.2005
Year:
2006
Pages from - to:
298-301
Language:
Englisch
Keywords:
Heavy ion cell irradiation ; Microbeam ; Protein dynamics ; γ-H2AX
Abstract:
Living HeLa cells are irradiated well directed with single 100 MeV oxygen ions by the superconducting ion microprobe SNAKE, the Superconducting Nanoscope for Applied Nuclear (=Kern-) Physics Experiments, at the Munich 14 MV tandem accelerator. Various proteins, which are involved directly or indirectly in repair processes, accumulate as clusters (so called foci) at DNA-double strand breaks (DSBs) induced by the ions. The spatiotemporal dynamics of these foci built by the phosphorylated histone γ... »
ISSN:
0168-583X
Department:
Fakultät für Luft- und Raumfahrttechnik
Institute:
LRT 2 - Institut für angewandte Physik und Messtechnik
Chair:
Dollinger, Günther
Open Access yes or no?:
Nein / No
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